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Filtered Search Results
Medchemexpress LLC Liothyronine-13C6-1 | 1213431-76-5 | 98.1% | C913C6H12I3NO4 | 100 UG
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Liothyronine-13C6-1 is a 13C-labeled Liothyronine, a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Fostemsavir Tris | 864953-39-9 | C29H37N8O11P | 10 MM/ML
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Fostemsavir Tris (BMS-663068 (Tris)) is a phosphonooxymethyl proagent of BMS-626529. This novel attachment inhibitor targets HIV-1 gp120, preventing its binding to CD4+ T cells. It demonstrates significant antiviral activity in subjects with susceptible viruses, making it a valuable compound for research applications.
- Targets HIV-1 gp120
- Prevents binding to CD4+ T cells
- Exhibits good antiviral activity
- Intended for research use
- Available as a solution in DMSO
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Medchemexpress LLC KNT-127 | 1256921-89-7 | 99.6% | 1 MG
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KNT-127 is a selective, brain-penetrant δ-opioid receptor agonist used in neuroscience research. It exhibits high affinity for the δ receptor and functional bias toward cAMP signaling, and has demonstrated antidepressant- and anxiolytic-like effects in animal models.
- Selective δ-opioid receptor agonist with high affinity (Ki δ ≈ 0.16 nM).
- Biased signaling toward cAMP over beta-arrestin pathways.
- Brain-penetrant compound suitable for in vivo studies.
- High purity solid (99.6%) available in milligram quantities.
- Recommended storage: powder at -20°C for long-term stability.
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Medchemexpress LLC Octadecanal | 638-66-4 | 268.48 | 5 G
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Octadecanal (Stearyl aldehyde) is a long-chain aldehyde component found in the phospholipid fractions of thigh and breast muscles of broiler chickens.
- White to off-white solid
- Store at -20°C under nitrogen
- In solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Classified as ketones, aldehydes, and acids
- Derived from endogenous metabolite
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Medchemexpress LLC (S)-(-)-Propranolol hydrochloride | 4199-10-4 | 100.0% | 10 MM 1 ML
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(S)-(-)-Propranolol hydrochloride is a chiral antihypertensive agent with approximately 100-fold higher potency than its R-enantiomer. It is used for studies on hypertension, angina pectoris, and arrhythmia. It appears as a white to off-white solid.
- Chiral antihypertensive agent
- Approximately 100-fold higher potency than its R-enantiomer
- Can be used for studies on hypertension, angina pectoris, and arrhythmia
- Exhibits enantiospecific SERS spectral features and peak intensity ratios when analyzed using an NPGB/EC-SERS platform, enabling label-free chiral differentiation
- For research use only
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Apexbio Technology LLC Adox, 25mg. Cas: 34240-05-6 MFCD: MFCD00063602. indirect methyltransferase inhibitor
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Adenosine dialdehyde (AdOx) has been identified as an indirect methyltransferase inhibitor. Histone methyltransferases are a group of enzymes that catalyze the methylation of histone lysine and arginine by adding methyl groups to specific histone arginine or lysine residues. Other sizes are available. Please inqury us for quote.
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Medchemexpress LLC Msx-127 | 6616-56-4 | 99.7% | 308.37 g/mol | C16H24N2O4 | 50 MG
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MSX-127 is a small-molecule CXCR4 antagonist used in preclinical research to study CXCR4-mediated signaling and the inhibition of cancer metastasis. Supplied as a high-purity solid for laboratory use; not for human or veterinary use.
- Small-molecule CXCR4 antagonist for receptor signaling studies.
- Used to investigate cancer metastasis and tumor cell migration.
- Purity 99.7% as reported by the supplier.
- Molecular weight 308.37 g/mol; formula C16H24N2O4.
- CAS number 6616-56-4 for compound identification.
- Supplied as a 50 mg solid for laboratory research.
- For research use only; not for human or veterinary use.
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Apexbio Technology LLC Rhodamine 123 (chloride) 62669-70-9 25mg
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Rhodamine 123 chloride (CAS 62669-70-9) is a cationic fluorescent dye targeting the mitochondrial membrane potential ( m) It is designed to selectively accumulate within the mitochondrial matrix by crossing the plasma membrane thus enabling detection of mitochondrial function and membrane integrity Rhodamine 123 chloride exerts its biological activity primarily by responding to changes in mitochondrial membrane potential producing yellow-green fluorescence upon accumulation in live-cell mitochondria In cell-based studies its fluorescence intensity directly reflects m but no specific IC50 or EC50 value or experimental cell line is reported Based on these properties Rhodamine 123 chloride holds research potential in measuring mitochondrial function assessing apoptosis evaluating ATP production and monitoring P-glycoprotein-mediated efflux in fluorescence microscopy and flow cytometry applications
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Apexbio Technology LLC Propranolol HCl 318-98-9 10mM (in 1mL DMSO)
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Propranolol HCl (CAS 318-98-9) is a small-molecule antagonist targeting 1- and 2-adrenergic receptors It is designed to competitively inhibit beta-adrenergic receptors thereby modulating sympathetic nervous system signaling Propranolol HCl exerts its biological activity primarily through competitive blockade of -adrenergic receptors preventing the binding of endogenous catecholamines In in vitro studies propranolol HCl demonstrates inhibitory activity with IC50 values typically within the range of 10 50 nM for -adrenoceptor binding assays Based on these pharmacological properties propranolol HCl holds research potential in cardiovascular regulatory studies neurotransmission models stress response experiments and tumor-related angiogenesis assays
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Medchemexpress LLC Propranolol glycol | 36112-95-5 | MFCD00673941 | 99.3% | 218.25 g/mol | C13H14O3 | 5 MG
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Propranolol glycol is an endogenous metabolite of propranolol that exhibits rapid anticonvulsant activity and is used as a research-grade analytical standard in studies of drug metabolism and pharmacology.
- Endogenous metabolite of propranolol.
- Instantaneous anticonvulsant activity reported in literature.
- High purity suitable for analytical and research use.
- Available in small-quantity formats for use as standards.
- Stable when stored under recommended conditions for reliable results.
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Medchemexpress LLC YBX1 protein, human (His) | >90.0% | 20UG
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Recombinant full-length human YBX1 protein with a C-terminal 6xHis tag, expressed in Escherichia coli and supplied lyophilized from PBS with 6% trehalose. Intended for research use in biochemical assays, binding studies, and detection workflows.
- Full-length human protein with C-terminal His tag.
- Expressed in Escherichia coli for bacterial expression systems.
- Lyophilized formulation for long-term storage.
- Purity greater than 90% by reducing SDS-PAGE.
- Predicted molecular mass 42.7 kDa; SDS-PAGE shows ~60 kDa band.
- Stable when stored at -20°C; reconstitute and aliquot for use.
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Medchemexpress LLC Niclosamide-13C6 | 1325808-64-7 | 99.0% | 5 MG
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Niclosamide-13C6 is the 13C6 labeled Niclosamide, an orally bioavailable chlorinated salicylanilide. It exhibits anthelmintic and potential antineoplastic activity, inhibiting STAT3 with an IC50 of 0.25 μM in HeLa cells and DNA replication in a cell-free assay. Stable heavy isotopes of carbon have been incorporated into this molecule, primarily for quantitation during drug development.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000697539 SADDNIKTPAEARG-13C6 5MG
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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